Figure 3: Effect of argon on the neuronal cell damage in the brain of SAH rats. Note: (A) Selected regions of interest. A high-power field was focused on five regions of interest in the left hippocampus (CA1, CA2, CA2/3 CA3, DG) and two in the left cortex (PLCo and PMCo) and one in the corpus callosum (CC). (B) Upper: Microglial activation depicted by Iba-1 staining (exemplary section of corpus callosum; yellow arrows: Iba-1 positive microglia); Lower: Neuronal cell damage in hematoxylin-eosin staining exemplary for DG comparing SAH vs. sham surgery (green arrows: vital neurons; red arrows: dead neurons). CA: Cornu ammonis; DG: dentate gyrus; Iba-1: ionized calcium-binding adapter molecule 1; PLCo: postero-lateral cortex; PMCo: postero-medial cortex; SAH: subarachnoid hemorrhage.