Medical Gas Research

RESEARCH ARTICLE
Year
: 2020  |  Volume : 10  |  Issue : 4  |  Page : 163--169

Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study


Amane Hori1, Sayaka Sobue2, Ryosuke Kurokawa3, Shin-ichi Hirano3, Masatoshi Ichihara4, Norio Hotta4 
1 Graduate School of Life and Health Sciences, Chubu University, Kasugai, Japan
2 College of Life and Health Sciences, Chubu University, Kasugai, Japan
3 MiZ Company Limited, Kamakura, Japan
4 Graduate School of Life and Health Sciences; College of Life and Health Sciences, Chubu University, Kasugai, Japan

Correspondence Address:
BA Amane Hori
Graduate School of Life and Health Sciences, Chubu University, Kasugai
Japan

The various beneficial effects of the intake of molecular hydrogen (H2) have been demonstrated in the field of sports science. Although supplementation of H2 has been reported to increase mitochondrial metabolism in animal studies, the effects of the administration of H2 on aerobic capacity during exercise in humans are still not clear. We investigated whether a single or 2-week continuous intake of H2-rich water (HW) enhanced the aerobic capacity during incremental exercise in healthy humans. In this randomized, single-blinded, placebo-controlled experimental study, the participants performed an incremental cycling exercise to measure peak oxygen uptake and peak load before and after a single (500 mL) or a 2-week supplementation (total 5 L) of HW. In the latter experiment, the participants drank the 500 mL of HW on all weekdays (i.e., 10 times). The single intake of HW did not significantly increase peak oxygen uptake and peak load, and did not significantly alter the responses in oxidative stress, antioxidant activity, and lactate levels. However, importantly, the 2-week continuous consumption of HW significantly augmented peak oxygen uptake and tended to increase the peak load without any significant changes in lactate levels, oxidative stress, and antioxidant responses. In conclusion, the continuous supplementation of HW potentially augments the aerobic capacity, implying that continuous supplementation of H2 might help improve aerobic exercise performance and physical health. This study protocol was approved by the Ethical Committee of Chubu University (approval No. 260086-2) on March 29, 2018.


How to cite this article:
Hori A, Sobue S, Kurokawa R, Hirano Si, Ichihara M, Hotta N. Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study.Med Gas Res 2020;10:163-169


How to cite this URL:
Hori A, Sobue S, Kurokawa R, Hirano Si, Ichihara M, Hotta N. Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study. Med Gas Res [serial online] 2020 [cited 2021 Jan 16 ];10:163-169
Available from: https://www.medgasres.com/article.asp?issn=2045-9912;year=2020;volume=10;issue=4;spage=163;epage=169;aulast=Hori;type=0