Figure 10: X-ray pictures with the position of Doppler wire, nitric oxide sensor and infusion catheter. Note: (A) Right anterior oblique (RAO) 30 μg acetylcholine, and (B) left anterior oblique (LAO) 60 μg acetylcholine. 7-Fr Amplatz guiding catheter was used to place the detection of nitric oxide (NO) sensor in the great cardiac vein from the femoral vein. A coronary-infusion catheter was positioned distal to the first major septal branch on the other hand Doppler guide wire was positioned distal to the infusion catheter to monitor coronary flow velocity.(C) NO concentration displayed in real-time profile and averaged peak velocity in the distal left anterior descending coronary artery (LAD). Adapted from Takarada et al.