Figure 2: Nitric oxide (NO) release kinetics of SNAP-PDMS films. Note: (A) The continuous NO release flux, taken at specified days while storing the films in phosphate buffer saline with ethylenediaminetetraacetic acid at 37°C (n = 4). The green line represents the minimum physiological level of NO flux (0.5 × 10-10 mol/(cm2•min)). (B) Cumulative NO release over the 125-day testing period, measured and normalized per cm2 of SNAP-PDMS. (C) Representative NO release profile on day 0 from SNAP-PDMS films when placed in phosphate buffer saline with ethylenediaminetetraacetic acid at 37°C. Reprinted with permission from Hopkins et al. SNAP: S-nitroso-N-acetylpenicillamine; PDMS: polydimethylsiloxane.