Figure 1: Body weight, SHIRPA score, and locomotor activity of mice with hydrogen gas inhaled. Note: (A) Body weight. (B) Total SHIRPA score. (C) locomotor activity score, a subset of the total SHIRPA score, which enumerates the number of squares that a mouse steps on within 30 seconds. (D) Post-exposure minus preexposure difference in locomotor activity score. Data are means, error is 95% confidence intervals in A–C; and the box represents the interquartile range, the whiskers the range, and the “+” the mean value in D. Data are analyzed by paired t-test or unpaired t-test. SHIRPA: SmithKline Beecham, Harwell, Imperial College, Royal London Hospital, Phenotype Assessment.