Figure 1: Effect of hydrogen-rich water (HRW) on the placental histopathological changes of placental stress rats induced by water restriction (hematoxylin and eosin staining). Note: In water restriction group (WR), the amnion epithelium was detached from the chorionic plate (★), there was a separation between endometrium and junctional zone (*), and dysangiogenesis was found in the villus interstitial (↑). The microstructure of placenta in the hydrogen-rich water group (HW) was relatively normal as compared with control group (CG). JZ: Junctional zone; LAB: placental labyrinth. Scale bars: 50 μm in placenta, 20 μm in JZ and LAB.