Figure 2: Susceptibility weighted imaging (SWI) identified hemorrhage lesion at 24 hours (hrs) post repetitive mild juvenile traumatic brain injury (rmjTBI). Note: (A) Representative SWI images revealed that hyperbaric oxygen (HBO) treatment resulted in less extravascular bleeding (hypointensity) within the traumatized brain tissue 24 hours after repetitive injury (arrows). Lines indicate the locations of craniotomy; (B) Quantifying SWI-derived hemorrhages volumes revealed that HBO decreased hemorrhagic susceptibility of mild injured brains to repetitive mild controlled cortical impact. Data are presented as the mean ± SEM. *P < 0.05, vs. sham group, #P < 0.05, vs. rmjTBI + HBO group (one-way analysis of variance followed by Student-Newman-Keuls post hoc test). mTBI: Mild traumatic brain injury.