Medical Gas Research

REVIEW
Year
: 2020  |  Volume : 10  |  Issue : 1  |  Page : 30--36

Neurocognitive sequelae after carbon monoxide poisoning and hyperbaric oxygen therapy


Ke Ning1, Yan-Yan Zhou2, Ning Zhang1, Xue-Jun Sun1, Wen-Wu Liu3, Cui-Hong Han4 
1 Department of Navy Aviation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai, China
2 Department of Orthopedic Surgery, Changzheng Hospital, Naval Medical University, Shanghai, China
3 Department of Diving and Hyperbaric Medicine, Naval Medical University, Shanghai, China
4 Department of Pathology, the Affiliated No 1 People's Hospital of Jining City, Jining Medical University, Jining, Shandong Province, China

Correspondence Address:
MD Cui-Hong Han
Department of Pathology, the Affiliated No 1 People's Hospital of Jining City, Jining Medical University, Jining, Shandong Province
China

Carbon monoxide (CO) has been the leading cause of poisoning mortality in many countries and hyperbaric oxygen (HBO) is a widely accepted treatment for CO poisoning. However, some patients with CO poisoning will still develop neurocognitive sequelae regardless of HBO therapy, which can persist since CO poisoning or be present days to weeks after a recovery from CO poisoning. HBO has been used in the prevention and treatment of neurocognitive sequelae after CO poisoning, and some mechanisms are also proposed for the potential neuroprotective effects of HBO on the neurocognitive impairment after CO poisoning, but there is still controversy on the effectiveness of HBO on neurocognitive sequelae after CO poisoning. In this paper, we briefly introduce the neurocognitive sequelae after CO poisoning, summarize the potential predictive factors of neurocognitive sequelae, and discuss the use of HBO in the treatment and prevention of neurocognitive sequelae after CO poisoning.


How to cite this article:
Ning K, Zhou YY, Zhang N, Sun XJ, Liu WW, Han CH. Neurocognitive sequelae after carbon monoxide poisoning and hyperbaric oxygen therapy.Med Gas Res 2020;10:30-36


How to cite this URL:
Ning K, Zhou YY, Zhang N, Sun XJ, Liu WW, Han CH. Neurocognitive sequelae after carbon monoxide poisoning and hyperbaric oxygen therapy. Med Gas Res [serial online] 2020 [cited 2020 May 28 ];10:30-36
Available from: http://www.medgasres.com/article.asp?issn=2045-9912;year=2020;volume=10;issue=1;spage=30;epage=36;aulast=Ning;type=0