• Users Online: 297
  • Home
  • Print this page
  • Email this page
REVIEW
Year : 2017  |  Volume : 7  |  Issue : 3  |  Page : 212-219

Ozone therapy: An overview of pharmacodynamics, current research, and clinical utility


1 Foley Plaza Medical, New York, NY, USA
2 Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, NY, USA
3 Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, NY, USA; Medical Student Research Institute, St. George's University School of Medicine, Grenada, West Indies
4 Department of Cardiothoracic Surgery, Lenox Hill Hospital, New York, NY, USA
5 Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, NY; Department of Urology, Stony Brook University School of Medicine, Stony Brook, NY, USA

Correspondence Address:
Sardar Ali Khan
Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, NY; Department of Urology, Stony Brook University School of Medicine, Stony Brook, NY
USA
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2045-9912.215752

Rights and Permissions

The use of ozone (O3) gas as a therapy in alternative medicine has attracted skepticism due to its unstable molecular structure. However, copious volumes of research have provided evidence that O3's dynamic resonance structures facilitate physiological interactions useful in treating a myriad of pathologies. Specifically, O3 therapy induces moderate oxidative stress when interacting with lipids. This interaction increases endogenous production of antioxidants, local perfusion, and oxygen delivery, as well as enhances immune responses. We have conducted a comprehensive review of O3 therapy, investigating its contraindications, routes and concentrations of administration, mechanisms of action, disinfectant properties in various microorganisms, and its medicinal use in different pathologies. We explore the therapeutic value of O3 in pathologies of the cardiovascular system, gastrointestinal tract, genitourinary system, central nervous system, head and neck, musculoskeletal, subcutaneous tissue, and peripheral vascular disease. Despite compelling evidence, further studies are essential to mark it as a viable and quintessential treatment option in medicine.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1533    
    Printed39    
    Emailed0    
    PDF Downloaded409    
    Comments [Add]    
    Cited by others 4    

Recommend this journal