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REVIEW
Year : 2016  |  Volume : 6  |  Issue : 4  |  Page : 219-222

Molecular hydrogen: a therapeutic antioxidant and beyond


Department of Anesthesiology, Loma Linda University, Loma Linda, CA; Department of Basic Sciences, Division of Physiology, Loma Linda University, Loma Linda, CA, USA

Correspondence Address:
Lei Huang
Department of Anesthesiology, Loma Linda University, Loma Linda, CA; Department of Basic Sciences, Division of Physiology, Loma Linda University, Loma Linda, CA
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2045-9912.196904

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Molecular hydrogen (H2 ) medicine research has flourished since a landmark publication in Nature Medicine that revealed the antioxidant and cytoprotective effects of hydrogen gas in a focal stroke model. Emerging evidence has consistently demonstrated that molecular hydrogen is a promising therapeutic option for a variety of diseases and the underlying comprehensive mechanisms is beyond pure hydroxyl radicals scavenging. The non-toxicity at high concentrations and rapid cellular diffusion features of molecular hydrogen ensure the feasibility and readiness of its clinical translation to human patients.


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